Serum Angiotensin Converting Enzyme in Patients with Psoriasis

Authors

  • Eshghi Gholamreza
  • Rahmati-Roudsari Mohammad
  • Saeedi Marjan
Abstract:

Background: Controversial data concerning the elevation of serum angiotensin-converting enzyme in psoriasis are reported in the literature. In order to verify whether this abnormality exists in Iranian patients, we performed this study. Method: Serum angiotensin-converting enzyme level was measured in 40 psoriatics. According to clinical forms of psoriasis, patients were further divided into three groups: common plaque type (n=24), pustular psoriasis (n=10) and erythrodermic psoriasis (n=6). Results: Serum angiotensin-converting enzyme shows some increase in patients with psoriasis; the greatest increase in serum angiotensinconverting enzyme level was observed in patients with erythrodermic psoriasis. Conclusion: Our results suggest that angiotensin-converting enzyme may have a role in the aetiopathogenesis of psoriasis but further studies are warranted to evaluate the possible role of this enzyme in psoriasis.

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Journal title

volume 12  issue 4

pages  127- 130

publication date 2009-12-01

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